Beginning at noon on Wednesday, August 28, the Tioga Road (Highway 120 through the park) is closed from Crane Flat to Yosemite Creek. The only access to the Tuolumne Meadows area is via Highway 120 from near Lee Vining.

Well if you have a permit going out of Tuolumne, Ten Lakes, or Yosemite Creek that makes it rather difficult to get there coming from the West side.

You can cross the Sierra north of Yosemite and come down 395.

Yeah, I know you can go 108 and come back from the east side, but that adds like 4 hours onto your trip

Quote
oakroscoe
Yeah, I know you can go 108

I wouldn't count on 108.

Ten Lakes is closed, the closure north of the Tioga Road extends eastward to the May Lake Road.

Yosemite News Release
Portion of Tioga Road in Yosemite National Park to be Temporarily Closed
Closure Needed to Support Firefighting Efforts in Park

Media Contacts:
Scott Gediman 209-372-0248
Kari Cobb 209-372-0529

A portion of the Tioga Road, from Crane Flat to White Wolf, will be temporarily closed to all vehicular traffic beginning tomorrow, Wednesday, August 28, 2013, at 12:00 noon. The closure is necessary for firefighters to perform fire suppression activities along the road. This portion of the road is anticipated to be closed at least through Labor Day Weekend. The park will issue an update as conditions allow for the reopening of the road.

“The work that will be performed over the next few days is instrumental in suppressing the Rim Fire within Yosemite. The safety of the firefighters working along the road is our paramount concern,” stated park Superintendent Don Neubacher.

Tamarack Flat and Yosemite Creek Campgrounds, both located along the Tioga Road within the closure, will remain closed during the fire suppression efforts. White Wolf Campground and White Wolf Lodge will remain closed. The Tioga Road will remain open east of White Wolf to the Tioga Pass Entrance. The Porcupine Flat Campground, the Tuolumne Meadows Campground, and all visitor services within Tuolumne Meadows will remain open.

Highway 41, from the southern portion of the park, and Highway 140, from the western portion of the park, will remain open. Both of these roads provide access to Yosemite Valley.

A fund to help the park restore trails, facilities, and wildlife habitat has been established by the Yosemite Conservancy. People wishing to contribute to the fund can donate online at http://yosemiteconservancy.org/fire. People can also donate via mail by sending donations to Yosemite Conservancy 101 Montgomery, Suite 1700 San Francisco, CA 95104.

For up-to-date Yosemite information regarding the Rim Fire, please visit the park’s website at: http://www.nps.gov/yose/planyourvisit/rimfire.htm.

They added a link to a closure map on the park's Rim Fire Page, but I think it's an old version of the map - it doesn't agree with the text. It shows a 'north-of-120-west-of-white-wolf' closure, while the text describes a 'north-of-north-rim-trail-west-of-may-lake' closure.