TBRF is a rare, but treatable and curable, bacterial infection that occurs in the western United States. People contract TBRF after being bitten by infected soft ticks, which typically feed on rodents. Bites from soft ticks are painless, brief (15 to 20 minutes), and usually happen at night when humans are asleep. Most infections are associated with sleeping in cabins in mountainous areas where rodents are present.
Common symptoms of TBRF include high fever (103-104°F; 39-40°C), headache, chills, and muscle aches. Nausea, vomiting, abdominal pain, and rash may also occur. TBRF is characterized by recurring ("relapsing"

There are usually less than 50 reported cases of TBRF in the United States annually. Though uncommon, two outbreaks have occurred on the North Rim of Grand Canyon in the last 42 years. In 1973, 62 cases were reported. In 1990, 17 cases were reported.
Individuals with travel history to the North Rim and symptoms consistent with TBRF should consult a healthcare provider and discuss potential exposures. TBRF is treatable with a commonly available antibiotic (doxycycline).