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dqniel
I used my Steripen in the Merced and I didn't die. I assume that's probably one of the dirtier streams in Yosemite?
I bought a SteriPen (Opti Adventurer, or somesuch) early last year and have used it since.
It has worked fine on snow melt, both stove-melted water and melt dripping off the side of a rock. It's worked fine on clear mountain streams, in CA, in Yellowstone, and in the Wind River Range.
I wouldn't use it where I expected to rely on glacial outflow, both because of the 'cloudy water' issue and because I don't want to chew water. That needs a field-cleanable filter.
I wouldn't use it on Isle Royale, or other areas with tapeworms that aren't killed by most devices. That, too, needs a filter.
I wouldn't use it on still water in Henry Coe SP, where I find the unfiltered lake water has an unpleasant algal taste. Likewise, I'd use a filter. That one's a choice rather than a requirement.
I wouldn't use it in Boundary Waters, where some of the water is heavily tannic...I'd take my MSR MIOX thingie.
Beyond those exceptions, I'd use my SteriPen.