I just got back to the Bay Area from Tahoe tonight. Somewhere just before Shingle Springs (might have been the southern end of Placerville), I saw a deer in the right lane (I was in the left). I was worried that it might move into the left lane, but it didn't and my GF's car was safe. However - a full-sized Dodge pickup collided straight on at the speed limit; I think the driver might not have even noticed until it was too late. I didn't see the actual impact, but man there was no escaping that sound like a gunshot. Later I got a quick look at the Dodge, and the bumper was hanging off at an angle showing clear damage. Eventually the driver got off at an exit with Highway Patrol office signage and I'm thinking he was going to report it.
I know deer and other animals in Yosemite meet similar ends, but there's nothing quite like it happening on a major divided highway with a 65 MPH speed limit.